No, really, how do cells and proteins stick to surfaces???



E. A. Vogler, Interfacial Chemistry in Biomaterial Science, in Wettability (Surfactant Science Series 49) Ed. J. Berg, Marcel Dekker: New York, pp. 184-250 (1993)..

E. A. Vogler, Structure and Reactivity of Water at Biomaterial Surfaces, Adv. Colloid and Interface Sci. 74, 69 (1998).

E. A. Vogler, Water and the Acute Biological Response to Surfaces, J. Biomat. Sci. Polym. Ed., 10, 1015 (1999).


Cell Adhesion:

J. Y. Lim, X. Liu, E. A. Vogler, H. J. Donahue, Systematic Variation in Osteoblast Adhesion and Phenotype with Substratum Surface Characteristics, J. Biomed. Mat. Res., 68A, 504 (2004).

E. A. Vogler and R. W. Bussian, Short-Term Cell-Attachment Rates: A Surface Sensitive Test of Cell-Substrate Compatibility, J. Biomed. Mat. Res., 21, 1197 (1987).

E. A. Vogler, Thermodynamics of Short-Term Cell Adhesion in Vitro, Biophysical J., 53, 759 (1988).

E. A. Vogler, A Thermodynamic Model of Short-Term Cell Adhesion In Vitro, Colloids and Surfaces, 42, 233 (1989).

S. Margel, E. A. Vogler, L. Firment, T. Watt, S. Haynie, and D. Y. Sogah, Peptide, Protein, and Cellular Interactions with Self-Assembled Monolayer Model Surfaces, J. Biomed. Mat. Res., 27, 1463 (1993).

A. L. Vinson, L. M. Lander, M. D. Foster, W. J. Brittain, E. A. Vogler, C. F. Majkrak, and S. Satija, A Neutron Reflectometry Study of Human Serum Albumin Adsorption in situ, Langmuir, 12, 2256 (1996).


                cartoon by Richard P. Clarke, 1989

Protein Adsorption:

A. Krishnan, C. A. Siedlecki, and E. A. Vogler, Traube-Rule Interpretation of Protein Adsorption at the Liquid-Vapor Interface, Langmuir, 19, 10342 (2003).

A. Krishnan, J. Sturgeon, C. A. Siedlecki, and E. A. Vogler, Scaled Interfacial Activity of Proteins at the Liquid-Vapor Interface, J. Biomed. Mat. Res., 68A, 544 (2004).

A. Krishnan, C. A. Siedlecki, and E. A. Vogler, Mixology of Protein Solutions and the Vroman Effect,  Langmuir, 20, 5071 (2004).